Live imaging reveals key cell dynamics in 3D organ formation in Drosophila
0
Animal development requires successive changes in cell and tissue structures. To form complex 3D organs, cell shapes must adapt to support tissue morphogenesis. However, our understanding of how cellular structure changes are coupled with dynamic tissue morphogenesis is limited, largely due to reliance on studies of fixed tissues and cultured cells. Real-time observation of cell shape changes during morphogenesis is therefore crucial.