by Christine Tara Peterson, Vandana Sharma, Stanislav N. Iablokov, Levent Albayrak, Kamil Khanipov, Sasha Uchitel, Deepak Chopra, Paul J. Mills, Yuriy Fofanov, Dmitry A. Rodionov, Scott N. Peterson
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by Isabelle Jalenques, Candy Guiguet-Auclair, Laurent Gerbaud, Chloé Rachez, Fabien Rondepierre
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by Surapathrudu Kanakala, Murad Ghanim
Bemisia tabaci is one of the most threatening pests in agriculture, causing significant losses to many important crops on a global scale. The dramatic increase and availability of sequence data for B. tabaci species complex and its bacterial endosymbionts is critical for developing emerging sustainable pest management strategies which are based on pinpointing the global diversity of this important pest and its bacterial endosymbionts. To unravel the global genetic diversity of B. Читать дальше...
by Sing Ying Wong, Onn Haji Hashim, Nobuhiro Hayashi
The primary components of human hair shaft—keratin and keratin-associated proteins (KAPs), together with their cross-linked networks—are the underlying reason for its rigid structure. It is therefore requisite to overcome the obstacle of hair insolubility and establish a reliable protocol for the proteome analysis of this accessible specimen. The present study employed an alkaline-based method for the efficient isolation of hair proteins... Читать дальше...
by Girish Kumar, Jorge Langa, Iratxe Montes, Darrell Conklin, Martin Kocour, Klaus Kohlmann, Andone Estonba
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by Giulia Tarquini, Giusi Zaina, Paolo Ermacora, Francesca De Amicis, Barbara Franco-Orozco, Nazia Loi, Marta Martini, Gian Luca Bianchi, Laura Pagliari, Giuseppe Firrao, Emanuele de Paoli, Rita Musetti
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by Christopher Negron, David A. Pearlman, Guillermo del Angel
Missense mutations can have disastrous effects on the function of a protein. And as a result, they have been implicated in numerous diseases. However, the majority of missense variants only have a nominal impact on protein function. Thus, the ability to distinguish these two classes of missense mutations would greatly aid drug discovery efforts in target identification and validation as well as medical diagnosis. Monitoring the... Читать дальше...
by Nicolas Narboux-Neme, Marc Ekker, Giovanni Levi, Eglantine Heude
Neural tube defects (NTDs), one of the most common birth defects in human, present a multifactorial etiology with a poorly defined genetic component. The Dlx5 and Dlx6 bigenic cluster encodes two evolutionary conserved homeodomain transcription factors, which are necessary for proper vertebrate development. It has been shown that Dlx5/6 genes are essential for anterior neural tube closure, however their role in the formation... Читать дальше...
by Marzieh Rostami Dovom, Nazanin Moslehi, Parvin Mirmiran, Fereidoun Azizi, Fahimeh Ramezani Tehrani
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by Anna Render, Petra Jansen
Sense of agency refers to the feeling of control over one’s own actions. The strength of this sense varies inter-individually. This means that people differ in their perception concerning the intensity of their intentions and actions. The current study aims to determine the factors influencing this sense of agency on a personality level. Furthermore, it gives insight into the correlative relation between the strength of the sense of agency and substance use. The... Читать дальше...
by Yeunhee Kwak, Yoonjung Kim, Kyoung Ah Baek
Irregular menstruation is an important indicator of current and potential health problems. A woman’s health is greatly influenced by her socioeconomic status. The purpose of this study was to examine the prevalence of irregular menstruation by socioeconomic status among South Korean women. Secondary data analyses were conducted among 4,709 women, aged 19–54 years, using raw data from the Korea National Health and Nutrition Examination Survey V (2010–2012), a nationally representative survey.
by Tadashi Ohara
BackgroundFecal microbiota transplantation (FMT) is an effective therapeutic approach for the treatment of functional gastrointestinal disease by restoring gut microbiota; however, there is a lack of sufficient understanding regarding which microbial populations successfully colonize the recipient gut. This study characterized microbial composition and diversity in patients diagnosed with chronic constipation at 1 month and 1 year after FMT.
MethodsWe explored... Читать дальше...
by Chih-Hsiung Hsieh, Chueh-Hsuan Lu, Yu-Yi Kuo, Guan-Bo Lin, Chih-Yu Chao
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by Suzan Murray, Jennifer C. Kishbaugh, Lee-Ann C. Hayek, Ilana Kutinsky, Patricia M. Dennis, William Devlin, Katharine L. Hope, Marietta D. Danforth, Hayley W. Murphy
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by Joanne Chia, Felicia Tay, Frederic Bard
The enzymes GALNTs add GalNAc sugar to Ser and Thr residues, forming the Tn glycan. GALNTs are activated by trafficking from Golgi to ER, a process driven by the Src kinase and negatively regulated by ERK8. This GALNTs activation (aka GALA) pathway induces high Tn levels and is a key driver of liver tumor growth. Recently, Tabak and colleagues have contested our previous data that EGF stimulation can induce GALNTs relocation. Here, we show that relocation... Читать дальше...
by Rachel J. Roth Flach, Chunyan Su, Eliza Bollinger, Christian Cortes, Andrew W. Robertson, Alan C. Opsahl, Timothy M. Coskran, Kevin P. Maresca, Edmund J. Keliher, Phillip D. Yates, Albert M. Kim, Amit S. Kalgutkar, Leonard Buckbinder
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by Blanca Navarrete, Antonio Leal-Morales, Laura Serrano-Ron, Marina Sarrió, Alicia Jiménez-Fernández, Lorena Jiménez-Díaz, Aroa López-Sánchez, Fernando Govantes
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by Charmaine Borg, Tamara A. Oosterwijk, Dominika Lisy, Sanne Boesveldt, Peter J. de Jong
by Yujin Lee, Dariush Mozaffarian, Stephen Sy, Yue Huang, Junxiu Liu, Parke E. Wilde, Shafika Abrahams-Gessel, Thiago de Souza Veiga Jardim, Thomas A. Gaziano, Renata Micha
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by Suvi Mäkeläinen, Marta Gòdia, Minas Hellsand, Agnese Viluma, Daniela Hahn, Karim Makdoumi, Caroline J. Zeiss, Cathryn Mellersh, Sally L. Ricketts, Kristina Narfström, Finn Hallböök, Björn Ekesten, Göran Andersson, Tomas F. Bergström
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by Josie L. Ferreira, Forson Z. Gao, Florian M. Rossmann, Andrea Nans, Susanne Brenzinger, Rohola Hosseini, Amanda Wilson, Ariane Briegel, Kai M. Thormann, Peter B. Rosenthal, Morgan Beeby
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