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2022

COVID-19 experts say Omicron is peaking in the US, citing data from poop samples

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There are some early indications that the Omicron wave may have already peaked, at least in poop, but the next 2-3 weeks are still going to be tough.

two men riding in toilet-shaped parade float
Yes, you really can measure how much COVID-19 is around by looking in our poo.
  • A network of more than 100 wastewater treatment plants across the US is measuring COVID-19 levels in our poop. 
  • Nationally, "the level of the virus in the wastewater is at a record high," one scientist said, which means there are more people in the US with COVID-19 right now than ever before.
  • The good news is that our poop data also suggests that the Omicron wave may be peaking right about now.

When Mariana Matus wants to know how bad the COVID-19 rates are where she lives, she looks to the poop. 

"It's crazy, but I do look at the wastewater data," the CEO and co-founder of Biobot Analytics told Insider. "That's what heavily informs the level of risk I'm willing to take, personally."

It may sound gross, but it's actually quite a sophisticated, science-backed early warning system for infectious disease surveillance. It's one that the Centers for Disease Control and Prevention is in the process of trying to scale up nationwide.

Matus's company is already monitoring COVID-19 rates among more than 100 waste treatment plants around the US, and keeping track of which variants are most prevalent where.

It's not an immediate, real-time warning system, but leading disease-watchers across the country are using the data as a reliable snapshot of how much virus people were flushing down the toilet about one week ago. 

That data, in turn, can give a good indication of how much coronavirus has been spreading around. And right now, the poop is telling us there is more COVID than ever getting passed around, and we may be reaching an all-time Omicron peak.

Why poop is a good tool for measuring COVID-19 levels

The reason that wastewater is such a valuable pandemic tool is because people who have COVID-19 poop it out.

Their deposits are not infectious — but they do turn PCR tests positive, in a similar way that throat and nose swabs do.

Since at-home COVID-19 tests are not always done correctly, and the results are not often recorded, tracking poop samples on a massive, population-wide scale is proving a much better tracking system.

To get their data, Matus's team conducts sampling at each treatment plant at least once a week, sampling near-continuously over the course of a 24-hour period. ("We assume everybody will use the toilet at least once" during that time, she said.)

Then they measure how much coronavirus is in the poop people have flushed out over the course of a day, compared to other, harmless viruses we excrete all the time.

"When the number of COVID-19-positive samples in sewage go up, 3 to 7 days later, the number of reported cases go up," CDC environmental engineer Mia Mattioli explained in an October blog post about the process

Right now, the poop forecast is telling us that there is COVID everywhere, and lots of it. 

Nationally, "the level of the virus in the wastewater is at a record high," Matus said. "It's the highest it's been throughout the pandemic, which indicates it's the most disease transmission that we have seen in the pandemic so far."

Matus lives in the Boston area, which currently has some of the most sophisticated publicly-available poop data, courtesy of her company, Biobot. (The state of Utah is one other US leader in COVID-19 poop data collection).

Early signals that Omicron infections are starting to decline, courtesy of our poo

In recent weeks, Boston's poop has been quite COVID-rich. In it, there are some early signals that infection rates are starting to decline from the recent all-time high:  

a graph of covid-19 levels in wastewater from boston, showing a big spike for omicron, then decrease

Matus says that what's happening in Boston mirrors what's beginning to happen nationally, too. 

If the trends continue, infection rates should decline sharply soon. 

"I still expect another one to two weeks of very high disease activity," Matus said. "The next two weeks we should be very, very careful." 

graph of how much covid 19 is in poop nationwide, showing rapid increase since omicron, appearing to crest now-ish.

Hospitalizations lag about three weeks behind the infection trends, and may not spike until February, either. 

The poop projections back up what infectious disease modelers from Texas to Washington are starting to project, too: that the current Omicron wave is slowing down.  

"The intense part should probably be over in many places in the month of January," Christopher Murray, lead modeler at the Institute for Health Metrics and Evaluation, said last week

Matus sees at-home tests, coupled with our poop data, as the future of comprehensive COVID-19 disease control.

"At-home tests are really important so people can make rapid decisions about themselves, their social activities, their level of social distancing and so on," she said. "And wastewater epidemiology data allows us to understand the true level of the pandemic."

What we flush away isn't just useful for tracking coronavirus infections, either. Poop data could also offer future insights into how widely influenza is circulating each year, or for discerning how much opioid drug use there is in a community. Our feces can reveal quite a lot about how healthy we are, making poop a rather useful public health barometer.

Read the original article on Business Insider




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